<![CDATA[Dr. K Elizabeth Reyes Marin: 🟢 Parietal Lobe – Integration & Protocols]]>https://neuroedgenexus.com/s/parietal-lobe-integration-and-protocolshttps://substackcdn.com/image/fetch/$s_!sq31!,w_256,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F98f4295c-d8f4-448c-aca3-d1f9863fe6ac_663x663.pngDr. K Elizabeth Reyes Marin: 🟢 Parietal Lobe – Integration & Protocolshttps://neuroedgenexus.com/s/parietal-lobe-integration-and-protocolsSubstackTue, 21 Apr 2026 08:05:42 GMT<![CDATA[Sleep as an Early Biomarker of Alzheimer’s Disease]]>https://neuroedgenexus.com/p/sleep-as-an-early-biomarker-of-alzheimershttps://neuroedgenexus.com/p/sleep-as-an-early-biomarker-of-alzheimersMon, 30 Mar 2026 14:02:42 GMTDOMAIN

Neuroscience & Alzheimer’s Prevention

SERIES EVOLUTION

Editions 21 → 22 → 23: From signals to biomarkers

Alzheimer’s disease does not begin with memory loss and the signal that precedes it may already be present every night, in the physiological record of how we sleep.

CLINICAL VIGNETTE

A 64-year-old neurologist presents for routine evaluation. Cognitive testing is normal. MRI is unremarkable. Blood biomarkers are within expected range. She reports no cognitive concerns.

Yet an overnight polysomnography recorded three years earlier shows a 22% reduction in slow-wave activity and increased sleep fragmentation compared to age-matched controls.

She has no diagnosis. No symptoms.

But the signal was there — recorded, timestamped, and not clinically interpreted.

Where this fits in NeuroEdge Nexus Series

Edition 21 established the body as data — demonstrating how digital biomarkers and wearable systems enable continuous physiological monitoring.

Edition 22 identified the translational bottlenec…

Read more

]]>