<![CDATA[Dr. K Elizabeth Reyes Marin: 🌐 Peripheral Nervous System – External Networks]]>https://neuroedgenexus.com/s/peripheral-nervous-system-externalhttps://substackcdn.com/image/fetch/$s_!sq31!,w_256,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F98f4295c-d8f4-448c-aca3-d1f9863fe6ac_663x663.pngDr. K Elizabeth Reyes Marin: 🌐 Peripheral Nervous System – External Networkshttps://neuroedgenexus.com/s/peripheral-nervous-system-externalSubstackTue, 21 Apr 2026 08:05:18 GMT<![CDATA[From Neural Signals to Patient Function: Why Neurotechnology Needs Systems, Not Just Science]]>https://neuroedgenexus.com/p/from-neural-signals-to-patient-functionhttps://neuroedgenexus.com/p/from-neural-signals-to-patient-functionSun, 22 Mar 2026 17:15:37 GMT

NeuroEdge Nexus — Edition 22 | March 2026

Neurotechnology is no longer limited by scientific discovery, but by the capacity of health systems to translate it into patient function.

A patient with cervical spinal cord injury sits in a rehabilitation unit. The science describing how to decode their motor cortex signals has been published. The engineering to translate those signals into robotic finger movements has been validated. A meta-analysis confirms clinical benefit exists. And yet the technology is not in the room. It never arrived. This is not a limitation of discovery. It is a structural constraint within current translational systems

— and it is the most important challenge in applied neurotechnology today.

Three studies published between 2024 and 2025 together describe, with unusual clarity, the full chain of what brain-computer interface (BCI) technology now makes possible. Read individually, each is a significant scientific contribution. Read together, they reveal something mor…

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]]><![CDATA[The Body as Data: How Digital Biomarkers Are Rewriting the Rules of Brain Health]]>https://neuroedgenexus.com/p/the-body-as-data-how-digital-biomarkershttps://neuroedgenexus.com/p/the-body-as-data-how-digital-biomarkersMon, 16 Mar 2026 08:00:57 GMTNeuroEdge Nexus — Edition 21 | March 2025

A brain does not malfunction on the day of diagnosis. In clinical and research settings, epileptiform activity detected on EEG, disrupted REM sleep architecture, and subtle gait alterations have each been observed in patients years before a formal diagnosis of neurodegeneration. In animal models of Alzheimer’s disease, epileptiform activity has been observed to precede cognitive decline. Emerging human studies suggest that continuous physiological monitoring may help detect similar early network alterations. The signal was always present. Only now are we building the instruments capable of reading it systematically.

Recent advances in digital biomarkers, wearable devices, artificial intelligence, and decentralized clinical trials are beginning to change how biological signals can be observed and interpreted. Instead of relying solely on periodic clinical measurements, researchers are increasingly exploring continuous physiological monitoring as …

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